Understanding Recombination

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Understanding the Biases of Generalised Recombination

In this paper we propose, model theoretically and study a general notion of recombination for fixed-length strings where homologous recombination, inversion, gene duplication, gene deletion, diploidy and more are just special cases. The analysis of the model reveals that the notion of schema emerges naturally from the model’s equations. The study provides a variety of fixed points for the case ...

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This is the first part of a two-part paper where we propose, model theoretically and study a general notion of recombination for fixed-length strings, where homologous recombination, inversion, gene duplication, gene deletion, diploidy and more are just special cases. The analysis of the model reveals that the notion of schema emerges naturally from the model's equations. In Part I, after descr...

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Meiosis is a specialized cell division, essential in most reproducing organisms to halve the number of chromosomes, thereby enabling the restoration of ploidy levels during fertilization. A key step of meiosis is homologous recombination, which promotes homologous pairing and generates crossovers (COs) to connect homologous chromosomes until their separation at anaphase I. These CO sites, seen ...

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ژورنال

عنوان ژورنال: Science

سال: 2012

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.338.6103.17-a